Semmes is located almost in the center of Mobile County and covers over 2100 acres. The Semmes area is bounded to the North by the City of Citronelle, bounded to the East by the City of Saraland and Prichard, bounded to the Southeast by the City of Mobile, and finally bounded to the West by Big Creek Lake.
Historically, the Semmes Community was founded around the railroad and The Semmes Land Company was incorporated in November, 1900. The railroad served an industrial purpose by transporting yellow pine from areas north of the community, as well as providing transportation services for passengers. The community was named for Admiral Raphael Semmes (1809-1877), an officer in the United States Navy from 1826 to 1860 and the Confederate States Navy from 1860 to 1865.